Mathieu Lachance

The genetic landscape of infantile spasms

Jacques L. Michaud, Mathieu Lachance, Fadi F. Hamdan et al. · Human Molecular Genetics · 2014 · 188 citations · Full text

Both gain‐of‐function and loss‐of‐function <i> de novo <scp>CACNA</scp> 1A </i> mutations cause severe developmental epileptic encephalopathies in the spectrum of Lennox‐Gastaut syndrome

Xiao Jiang, Praveen K. Raju, Nazzareno D’Avanzo et al. · Epilepsia · 2019 · 93 citations

Remodeled cortical inhibition prevents motor seizures in generalized epilepsy

Xiao Jiang, Alexis Lupien‐Meilleur, Sabrina Tazerart et al. · Annals of Neurology · 2018 · 41 citations

Reversing frontal disinhibition rescues behavioural deficits in models of CACNA1A-associated neurodevelopment disorders

Alexis Lupien‐Meilleur, Xiao Jiang, Mathieu Lachance et al. · Molecular Psychiatry · 2021 · 31 citations

Neurodevelopmental Disorders, Neuropsychological Functioning, Cognitive Science +10

Stimulation-induced ectopicity and propagation windows in model damaged axons

Mathieu Lachance, André Longtin, Catherine E. Morris et al. · Journal of Computational Neuroscience · 2014 · 17 citations · Full text

Anesthetic Mechanism, Propagation Windows, Neurotransmission +16