James Sun

Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden

Zachary R. Chalmers, Caitlin Connelly, David Fabrizio et al. · Genome Medicine · 2017 · 3.7K citations · Full text

Medicine, Cancer Biology, Oncology +17

Development and validation of a clinical cancer genomic profiling test based on massively parallel DNA sequencing

Garrett M. Frampton, Alex Fichtenholtz, Geoff Otto et al. · Nature Biotechnology · 2013 · 2.2K citations · Full text

Medicine, Genetics, Oncology +14

Emergence of Constitutively Active Estrogen Receptor-α Mutations in Pretreated Advanced Estrogen Receptor–Positive Breast Cancer

Rinath Jeselsohn, Roman Yelensky, Gilles Buchwalter et al. · Clinical Cancer Research · 2014 · 662 citations

Medicine, Genetics, Oncology +17

Comprehensive Genomic Profiling of 282 Pediatric Low- and High-Grade Gliomas Reveals Genomic Drivers, Tumor Mutational Burden, and Hypermutation Signatures

Adrienne Johnson, Eric A. Severson, Laurie M. Gay et al. · The Oncologist · 2017 · 289 citations · Full text

Medicine, Genetics, Oncology +17

A computational approach to distinguish somatic vs. germline origin of genomic alterations from deep sequencing of cancer specimens without a matched normal

James Sun, Yuting He, Eric M. Sanford et al. · PLoS Computational Biology · 2018 · 286 citations · Full text

Medicine, Genetics, Oncology +17