Chengbin Yang

Discovery of a Novel Series of 7-Azaindole Scaffold Derivatives as PI3K Inhibitors with Potent Activity

Chengbin Yang, Xi Zhang, Yi Wang et al. · ACS Medicinal Chemistry Letters · 2017 · 32 citations · Full text

Polydatin (PD) inhibits IgE-mediated passive cutaneous anaphylaxis in mice by stabilizing mast cells through modulating Ca2+ mobilization

Mei-Chun Yuan, Jianjie Li, Lv JingZhang et al. · Toxicology and Applied Pharmacology · 2012 · 26 citations

Inflammation, Allergy, Autoimmune Disease +11

Bioisosteric replacements of the indole moiety for the development of a potent and selective PI3Kδ inhibitor: Design, synthesis and biological evaluation

Chengbin Yang, Chenyue Xu, Zhipeng Li et al. · European Journal of Medicinal Chemistry · 2021 · 21 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +11

Discovery of cinnoline derivatives as potent PI3K inhibitors with antiproliferative activity

Chengze Tian, Chengbin Yang, Tianze Wu et al. · Bioorganic & Medicinal Chemistry Letters · 2021 · 19 citations · Full text

Medicinal Chemistry, Biochemistry, Antiproliferative Activity +12

Development of anti-breast cancer PI3K inhibitors based on 7-azaindole derivatives through scaffold hopping: Design, synthesis and in vitro biological evaluation

Chengbin Yang, Mingzhu Lu, Yi Chen et al. · Bioorganic Chemistry · 2021 · 18 citations

Combinatorial Chemistry, Medicinal Chemistry, Scaffold Hopping +8