Karl Syson

Self-poisoning of Mycobacterium tuberculosis by targeting GlgE in an α-glucan pathway

Rainer Kalscheuer, Karl Syson, Veeraraghavan Usha et al. · Nature Chemical Biology · 2010 · 157 citations

Medical Microbiology, Pulmonary Tuberculosis, Tuberculosis Prevention +8

Metabolic Network for the Biosynthesis of Intra- and Extracellular α-Glucans Required for Virulence of Mycobacterium tuberculosis

Hendrik Koliwer‐Brandl, Karl Syson, Robert van de Weerd et al. · PLoS Pathogens · 2016 · 65 citations · Full text

Microbial Pathogens, Bacteriology, Glycobiology +16

Structure of Streptomyces Maltosyltransferase GlgE, a Homologue of a Genetically Validated Anti-tuberculosis Target

Karl Syson, Clare E. M. Stevenson, Martin Rejzek et al. · Journal of Biological Chemistry · 2011 · 61 citations · Full text

Assembly of α-Glucan by GlgE and GlgB in Mycobacteria and Streptomycetes

Abdul Rashid, Sibyl F. D. Batey, Karl Syson et al. · Biochemistry · 2016 · 41 citations · Full text

Protein Glycosylation, Biosynthesis, Engineering +14

Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice

Jan Korte, Marina Alber, Carolina Trujillo et al. · PLoS Pathogens · 2016 · 38 citations · Full text

Pulmonary Tuberculosis, Biosynthesis, Cellular Enzymology +13