Structure‐Based Repurposing of FDA‐Approved Drugs as TNF‐α Inhibitors

Chung‐Hang Leung, Daniel Shiu‐Hin Chan, Maria Hiu‐Tung Kwan, +5

ChemMedChem

Chemical Structure and Immunomodulating Activities of an α-Glucan Purified from Lobelia chinensis Lour

Xiaojun Li, Wan-Rong Bao, Chung‐Hang Leung, +5

Molecules

GlycosylationBiochemistryLobelia Chinensis LourLobelia ChinensisMedicine +13

Structure-based repurposing of FDA-approved drugs as inhibitors of NEDD8-activating enzyme

Hai‐Jing Zhong, Lijuan Liu, Daniel Shiu‐Hin Chan, +4

Biochimie

Drug RepositioningBiochemistryMedicineNatural SciencesRational Drug Design +5

Antagonism of mTOR Activity by a Kinetically Inert Rhodium(III) Complex

Hai‐Jing Zhong, Ka‐Ho Leung, Lijuan Liu, +4

ChemPlusChem

Radix Astragali polysaccharide RAP directly protects hematopoietic stem cells from chemotherapy-induced myelosuppression by increasing FOS expression

Wan-Rong Bao, Quanwei Zhang, Hongming Zheng, +10

International Journal of Biological Macromolecules

Chemotherapy-induced MyelosuppressionMedicineStem Cell MobilizationHematologyImmunology +8

Aberrant JAK/STAT Signaling Suppresses TFF1 and TFF2 through Epigenetic Silencing of GATA6 in Gastric Cancer

Cheng-Shyong Wu, Kuo‐Liang Wei, Jian‐Liang Chou, +10

International Journal of Molecular Sciences

Epigenetic SilencingTumor BiologySystems BiologyGastrointestinal OncologyMedicine +12

Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening

Ka‐Ho Leung, Lijuan Liu, Sheng Lin, +10

Methods

Medicinal ChemistryBiochemistryMedicineNatural SciencesPharmacotherapy +7

Silver Triflate Catalyzed Cyclopropyl Carbinol Rearrangement for Benzo[<i>b</i>]oxepine and 2<i>H</i>‐Chromene Synthesis

Philip Wai Hong Chan, Wan Teng Teo, Shaun Wei Yong Koh, +4

European Journal of Organic Chemistry

Chemical EngineeringEngineeringAlkene MetathesisProduct SelectivityNatural Sciences +8

An oligosaccharide-marker approach to quantify specific polysaccharides in herbal formula by LC-qTOF-MS: Danggui Buxue Tang, a case study

Lifeng Li, Tin-Long Wong, Jixia Zhang, +13

Journal of Pharmaceutical and Biomedical Analysis

Specific PolysaccharidesEngineeringBioassay-guided IsolationMedicineNutraceutical Ingredient +10

The Impact of Hypoxic Treatment on the Expression of Phosphoglycerate Kinase and the Cytotoxicity of Troxacitabine and Gemcitabine

Wing Lam, Chung‐Hang Leung, Scott Bussom, +1

Molecular Pharmacology