Wenchang Guo

Formation of 17-Allylamino-Demethoxygeldanamycin (17-AAG) Hydroquinone by NAD(P)H:Quinone Oxidoreductase 1: Role of 17-AAG Hydroquinone in Heat Shock Protein 90 Inhibition

Wenchang Guo, Philip Reigan, David Siegel et al. · Cancer Research · 2005 · 173 citations

HSP90 Inhibitor Encapsulated Photo-Theranostic Nanoparticles for Synergistic Combination Cancer Therapy

Tzu‐yin Lin, Wenchang Guo, Qilai Long et al. · Theranostics · 2016 · 82 citations · Full text

Enzymatic Reduction and Glutathione Conjugation of Benzoquinone Ansamycin Heat Shock Protein 90 Inhibitors: Relevance for Toxicity and Mechanism of Action

Wenchang Guo, Philip Reigan, David Siegel et al. · Drug Metabolism and Disposition · 2008 · 64 citations · Full text

EGFR signaling-dependent inhibition of glioblastoma growth by ginsenoside Rh2

Shaoyi Li, Yun Gao, Weining Ma et al. · Tumor Biology · 2014 · 63 citations

The Bioreduction of a Series of Benzoquinone Ansamycins by NAD(P)H:Quinone Oxidoreductase 1 to More Potent Heat Shock Protein 90 Inhibitors, the Hydroquinone Ansamycins

Wenchang Guo, Philip Reigan, David Siegel et al. · Molecular Pharmacology · 2006 · 60 citations