Ancestral Origins of the Machado-Joseph Disease Mutation: A Worldwide Haplotype Study

Cláudia Gaspar, Íscia Lopes‐Cendes, Sean M. Hayes, +24

The American Journal of Human Genetics

Ancestral OriginsGenetic DisorderGeneticsEvolutionary BiologyGenetic Variation +6

Decreased antioxidant enzyme activity and increased mitochondrial DNA damage in cellular models of Machado‐Joseph disease

Ya‐Chun Yu, Chen‐Ling Kuo, Wen‐Ling Cheng, +2

Journal of Neuroscience Research

Asian Origin for the Worldwide-Spread Mutational Event in Machado-Joseph Disease

Sandra Martins, Francesc Calafell, Cláudia Gaspar, +19

Archives of Neurology

Asian OriginMolecular EpidemiologyGeneticsGenetic EpidemiologyPathology +25

Functional Recovery of Human Cells Harbouring the Mitochondrial DNA Mutation MERRF <b><i>A8344G</i></b> via Peptide-Mediated Mitochondrial Delivery

Jui‐Chih Chang, Ko‐Hung Liu, Yuchi Li, +5

Neurosignals

MitophagyGeneticsMolecular BiologyCell DeathMolecular Genetics +24

Caffeic acid and resveratrol ameliorate cellular damage in cell and Drosophila models of spinocerebellar ataxia type 3 through upregulation of Nrf2 pathway

Yu‐Ling Wu, Jui‐Chih Chang, Wei‐Yong Lin, +7

Free Radical Biology and Medicine

Reductive StressNrf2 PathwayMedicineLipid PeroxidationCell Death +8

Down‐regulation of heat shock protein 27 in neuronal cells and non‐neuronal cells expressing mutant ataxin‐3

Feng-Chen Wen, Yen-Hsien Li, Hui-Fang Tsai, +6

FEBS Letters

Analysis of trinucleotide repeats in different SCA loci in spinocerebellar ataxia patients and in normal population of Taiwan

Hui-Fang Tsai, Chin-San Liu, Tsong-Ming Leu, +6

Acta Neurologica Scandinavica

Full-length expanded ataxin-3 enhances mitochondrial-mediated cell death and decreases Bcl-2 expression in human neuroblastoma cells

Hui‐Fang Tsai, Horng-Jyh Tsai, Mingli Hsieh

Biochemical and Biophysical Research Communications

Mitochondrial FunctionApoptosisImmunologyCell DeathHuman Neuroblastoma Cells +5

Far-infrared radiation protects viability in a cell model of Spinocerebellar Ataxia by preventing polyQ protein accumulation and improving mitochondrial function

Jui‐Chih Chang, Shey‐Lin Wu, Fredrik Hoel, +11

Scientific Reports

Decreased expression of Hsp27 and Hsp70 in transformed lymphoblastoid cells from patients with spinocerebellar ataxia type 7

Hui‐Fang Tsai, Shio Jean Lin, Chuan Li, +1

Biochemical and Biophysical Research Communications

Neurodegenerative DiseasesMolecular NeuroscienceTransformed Lymphoblastoid CellsSpinocerebellar AtaxiaNeurology +3