LysGH15, a Novel Bacteriophage Lysin, Protects a Murine Bacteremia Model Efficiently against Lethal Methicillin-Resistant <i>Staphylococcus aureus</i> Infection

Jingmin Gu, Wei Xu, Liancheng Lei, +9

Journal of Clinical Microbiology

Structural and Biochemical Characterization Reveals LysGH15 as an Unprecedented “EF-Hand-Like” Calcium-Binding Phage Lysin

Jingmin Gu, Yingang Feng, Xin Feng, +16

PLoS Pathogens

Protein ChemistryCrystal StructureProtein FunctionProtein AssemblyBiochemistry +9

Genipin inhibits NLRP3 and NLRC4 inflammasome activation via autophagy suppression

Shui-Xing Yu, Chongtao Du, Wei Chen, +8

Scientific Reports

Microbial PathogensImmunologyImmune RegulationCell DeathNlrc4 Inflammasomes +23

Enolase of Streptococcus Suis Serotype 2 Enhances Blood–Brain Barrier Permeability by Inducing IL-8 Release

Yingying Sun, Na Li, Jing Zhang, +9

Inflammation

InflammationMicrobial PathogensBlood–brain BarrierMedicinePathogenesis +9

A guard-killer phage cocktail effectively lyses the host and inhibits the development of phage-resistant strains of Escherichia coli

Ling Yu, Shuang Wang, Zhimin Guo, +10

Applied Microbiology and Biotechnology

Antimicrobial SusceptibilityBacteriophageEscherichia ColiPhage-resistant StrainsMicrobiology +4

Vomiting and wasting disease associated with hemagglutinating encephalomyelitis viruses infection in piglets in jilin, china

Wei Gao, Kui Zhao, Chuanbo Zhao, +10

Virology Journal

The antibacterial activity of E. coli bacteriophage lysin lysep3 is enhanced by fusing the Bacillus amyloliquefaciens bacteriophage endolysin binding domain D8 to the C-terminal region

Shuang Wang, Jingmin Gu, Meng Lv, +8

The Journal of Microbiology

Therapeutic effect of the YH6 phage in a murine hemorrhagic pneumonia model

Mei Yang, Chongtao Du, Pengjuan Gong, +13

Research in Microbiology

Translational MedicineTherapeutic EffectMedicineImmunologyYh6 Phage +2

Adh enhances Actinobacillus pleuropneumoniae pathogenicity by binding to OR5M11 and activating p38 which induces apoptosis of PAMs and IL-8 release

Lei Wang, Wanhai Qin, Jing Zhang, +10

Scientific Reports

Inflammatory Lung DiseaseMicrobial PathogensLung InflammationApoptosisImmunology +25

MicroRNA-146a Deficiency Protects against Listeria monocytogenes Infection by Modulating the Gut Microbiota

Chongtao Du, Wei Gao, Ke Ma, +9

International Journal of Molecular Sciences