Linyuan Peng

Synergy between SIRT1 and SIRT6 helps recognize DNA breaks and potentiates the DNA damage response and repair in humans and mice

Fanbiao Meng, Minxian Qian, Bin Peng et al. · eLife · 2020 · 86 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria

Minxian Qian, Zuojun Liu, Linyuan Peng et al. · eLife · 2018 · 79 citations · Full text

Education, Biology, Molecular Biology +17

Deacetylase-independent function of SIRT6 couples GATA4 transcription factor and epigenetic activation against cardiomyocyte apoptosis

Linyuan Peng, Minxian Qian, Zuojun Liu et al. · Nucleic Acids Research · 2020 · 64 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

A Glb1-2A-mCherry reporter monitors systemic aging and predicts lifespan in middle-aged mice

Jie Sun, Ming Wang, Yaqi Zhong et al. · Nature Communications · 2022 · 43 citations · Full text

Education, Biochemistry, Molecular Biology +17

Lamin A safeguards the m⁶A methylase METTL14 nuclear speckle reservoir to prevent cellular senescence

Jie Zhang, Ao Ying, Zhen Zhang et al. · Aging Cell · 2020 · 38 citations · Full text

Life Sciences, Genetics, Molecular Biology +17