Hsien‐Chun Chiu

Metformin-mediated downregulation of p38 mitogen-activated protein kinase-dependent excision repair cross-complementing 1 decreases DNA repair capacity and sensitizes human lung cancer cells to paclitaxel

Sheng-Chieh Tseng, Yu‐Ching Huang, Huang-Jen Chen et al. · Biochemical Pharmacology · 2012 · 53 citations

Medicine, Oncology, Pharmacology +11

Preventing muscle wasting by osteoporosis drug alendronate <i>in vitro</i> and in myopathy models via sirtuin‐3 down‐regulation

Hsien‐Chun Chiu, Chen‐Yuan Chiu, Rong‐Sen Yang et al. · Journal of Cachexia Sarcopenia and Muscle · 2018 · 47 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17

Tamoxifen enhances erlotinib-induced cytotoxicity through down-regulating AKT-mediated thymidine phosphorylase expression in human non-small-cell lung cancer cells

Jen‐Chung Ko, Hsien‐Chun Chiu, Jhan‐Jhang Syu et al. · Biochemical Pharmacology · 2014 · 30 citations

Medicine, Oncology, Pharmacology +16

HSP90 inhibition induces cytotoxicity via down-regulation of Rad51 expression and DNA repair capacity in non-small cell lung cancer cells

Jen‐Chung Ko, Huang-Jen Chen, Yu‐Ching Huang et al. · Regulatory Toxicology and Pharmacology · 2012 · 28 citations

Life Sciences, Molecular Biology, Oncology +13

Inhibition of p38 MAPK-dependent MutS homologue-2 (MSH2) expression by metformin enhances gefitinib-induced cytotoxicity in human squamous lung cancer cells

Jen‐Chung Ko, Hsien‐Chun Chiu, Ting‐Yu Wo et al. · Lung Cancer · 2013 · 22 citations

Medicine, Oncology, Pharmacology +12