Junkai Yan

Boosting mTOR-dependent autophagy via upstream TLR4-MyD88-MAPK signalling and downstream NF-κB pathway quenches intestinal inflammation and oxidative stress injury

Mingxia Zhou, Weimin Xu, Jiazheng Wang et al. · EBioMedicine · 2018 · 349 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Curcumin alleviates DSS-induced colitis via inhibiting NLRP3 inflammsome activation and IL-1β production

Zizhen Gong, Shengnan Zhao, Jiefei Zhou et al. · Molecular Immunology · 2018 · 207 citations

Life Sciences, Immunology, Pathobiology +11

Neutralization of IL-6 and TNF-α ameliorates intestinal permeability in DSS-induced colitis

Yongtao Xiao, Weihui Yan, Yi Cao et al. · Cytokine · 2016 · 192 citations

Life Sciences, Immunology, Pathology +14

Discovery of Tryptanthrin Derivatives as Potent Inhibitors of Indoleamine 2,3-Dioxygenase with Therapeutic Activity in Lewis Lung Cancer (LLC) Tumor-Bearing Mice

Shuangshuang Yang, Xishuai Li, Fangfang Hu et al. · Journal of Medicinal Chemistry · 2013 · 181 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

The IDO Inhibitor Coptisine Ameliorates Cognitive Impairment in a Mouse Model of Alzheimer's Disease

Dan Yu, Bangbao Tao, Yunyun Yang et al. · Journal of Alzheimer s Disease · 2014 · 102 citations

Medicine, Neuroscience, Pharmacology +17