Xu Zhang

Dexmedetomidine attenuates propofol-induce neuroapoptosis partly via the activation of the PI3k/Akt/GSK3β pathway in the hippocampus of neonatal rats

Jing Lv, Yi Wei, Yanhua Chen et al. · Environmental Toxicology and Pharmacology · 2017 · 58 citations

Medicine, Neuroscience, Pharmacology +13

Isoalantolactone inhibits LPS-induced inflammation via NF-κB inactivation in peritoneal macrophages and improves survival in sepsis

Guodong He, Xu Zhang, Yanhua Chen et al. · Biomedicine & Pharmacotherapy · 2017 · 49 citations

Life Sciences, Immunology, Pharmacology +16

Dexmedetomidine reduces the neuronal apoptosis related to cardiopulmonary bypass by inhibiting activation of the JAK2–STAT3 pathway

Yanhua Chen, Xu Zhang, Bingdong Zhang et al. · Drug Design Development and Therapy · 2017 · 29 citations · Full text

Medicine, Neuroscience, Pharmacology +15

Dexmedetomidine attenuates the propofol-induced long-term neurotoxicity in the developing brain of rats by enhancing the PI3K/Akt signaling pathway

Yong Xiao, Lifang Zhou, Youbing Tu et al. · Neuropsychiatric Disease and Treatment · 2018 · 26 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Effect of different administration and dosage of dexmedetomidine in the reduction of emergence agitation in children: a meta-analysis of randomized controlled trials with sequential trial analysis

Xu Zhang, Yan Bai, Min Shi et al. · Translational Pediatrics · 2021 · 21 citations · Full text

Medicine, Pediatrics, Pharmacology +13