Concepedia
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Publications
8
Citations
414
H-Index
Active since
2004
Affiliations
Markey Cancer Center(Current)
University of Kentucky
Center for Excellence in Molecular Cell Science
Chinese Academy of Sciences
Shanghai Institutes for Biological Sciences
Junkai Fan is an author at Markey Cancer Center specializing in medicine, cell signaling, and cell biology.
Top concepts
MedicineCell BiologyCell SignalingSignal TransductionCell PhysiologyDevelopmental BiologyNatural SciencesMolecular BiologyCellular BiochemistryBiochemistry
Publications per year
2004–2016
USP8 Promotes Smoothened Signaling by Preventing Its Ubiquitination and Changing Its Subcellular Localization
Ruohan Xia, Hongge Jia, Junkai Fan et al. · PLoS Biology · 2012 · 125 citations · Full text
Signal Transduction, Developmental Biology, Usp8 Promotes +15
PI(4)P Promotes Phosphorylation and Conformational Change of Smoothened through Interaction with Its C-terminal Tail
Kai Jiang, Yajuan Liu, Junkai Fan et al. · PLoS Biology · 2016 · 77 citations · Full text
C-terminal Tail, Molecular Biology, Arginine Motif +21
Herpes virus proteins ICP0 and BICP0 can activate NF-κB by catalyzing IκBα ubiquitination
Lirong Diao, Bianhong Zhang, Junkai Fan et al. · Cellular Signalling · 2004 · 71 citations
Signal Transduction, Viral Pathogenesis, Immunology +7
Hh-induced Smoothened conformational switch is mediated by differential phosphorylation at its C-terminal tail in a dose- and position-dependent manner
Junkai Fan, Yajuan Liu, Jianhang Jia · Developmental Biology · 2012 · 44 citations · Full text
Biophysical Modeling, Signal Transduction, Biochemistry +13
Hedgehog-regulated atypical PKC promotes phosphorylation and activation of Smoothened and Cubitus interruptus in <i>Drosophila</i>
Kai Jiang, Yajuan Liu, Junkai Fan et al. · Proceedings of the National Academy of Sciences · 2014 · 37 citations · Full text
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