Concepedia

Junkai Fan

JF

8

Publications

414

Citations

8

H-Index

2004

Active since

Affiliations

Markey Cancer Center(Current)

University of Kentucky

Center for Excellence in Molecular Cell Science

Chinese Academy of Sciences

Shanghai Institutes for Biological Sciences

Junkai Fan is an author at Markey Cancer Center specializing in medicine, cell signaling, and cell biology.

Top concepts

MedicineCell BiologyCell SignalingSignal TransductionCell PhysiologyDevelopmental BiologyNatural SciencesMolecular BiologyCellular BiochemistryBiochemistry

Publications per year

2004–2016

8

Publications

8

USP8 Promotes Smoothened Signaling by Preventing Its Ubiquitination and Changing Its Subcellular Localization

Ruohan Xia, Hongge Jia, Junkai Fan et al. · PLoS Biology · 2012 · 125 citations · Full text

Signal Transduction, Developmental Biology, Usp8 Promotes +15

PI(4)P Promotes Phosphorylation and Conformational Change of Smoothened through Interaction with Its C-terminal Tail

Kai Jiang, Yajuan Liu, Junkai Fan et al. · PLoS Biology · 2016 · 77 citations · Full text

C-terminal Tail, Molecular Biology, Arginine Motif +21

Herpes virus proteins ICP0 and BICP0 can activate NF-κB by catalyzing IκBα ubiquitination

Lirong Diao, Bianhong Zhang, Junkai Fan et al. · Cellular Signalling · 2004 · 71 citations

Signal Transduction, Viral Pathogenesis, Immunology +7

Hh-induced Smoothened conformational switch is mediated by differential phosphorylation at its C-terminal tail in a dose- and position-dependent manner

Junkai Fan, Yajuan Liu, Jianhang Jia · Developmental Biology · 2012 · 44 citations · Full text

Biophysical Modeling, Signal Transduction, Biochemistry +13

Hedgehog-regulated atypical PKC promotes phosphorylation and activation of Smoothened and Cubitus interruptus in <i>Drosophila</i>

Kai Jiang, Yajuan Liu, Junkai Fan et al. · Proceedings of the National Academy of Sciences · 2014 · 37 citations · Full text

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