Shuichi Kojima

Methylene Blue Inhibits Formation of Tau Fibrils but not of Granular Tau Oligomers: A Plausible Key to Understanding Failure of a Clinical Trial for Alzheimer’s Disease

Yoshiyuki Soeda, Marino Saito, Sumihiro Maeda et al. · Journal of Alzheimer s Disease · 2019 · 81 citations

Fibril Formation by an Amphipathic .ALPHA.-Helix-Forming Polypeptide Produced by Gene Engineering.

Shuichi Kojima, Yukino Kuriki, Takao Yoshida et al. · Proceedings of the Japan Academy Series B · 1997 · 58 citations · Full text

Gene Engineering, Salt Concentration, Engineering +23

Molecular recognition at the active site of subtilisin BPN': crystallographic studies using genetically engineered proteinaceous inhibitor SSI (<i>Streptomyces</i> subtilisin inhibitor)

Yasuo Takeuchi, Shuji Noguchi, Yoshinori Satow et al. · Protein Engineering Design and Selection · 1991 · 54 citations

Protein Assembly, Biomolecular Structure Prediction, Molecular Biology +17

Inhibition of Subtilisin BPN′ by Reaction Site P1 Mutants of Streptomyces Subtilisin Inhibitor1

Shuichi Kojima, Yoshitaka Nishiyama, Izuml Kumagai et al. · The Journal of Biochemistry · 1991 · 43 citations

Requirement for a Disulfide Bridge Near the Reactive Site of Protease Inhibitor SSI (Streptomyces Subtilisin Inhibitor) for its Inhibitory Action

Shuichi Kojima, Izumi Kumagai, Kin‐ichiro Miura · Journal of Molecular Biology · 1993 · 42 citations

Biochemistry, Natural Sciences, Protease Inhibitor Ssi +9