Decreased FOXP3 levels in multiple sclerosis patients

Jianya Huan, Nicole Culbertson, Leslie Spencer, +7

Journal of Neuroscience Research

RNA Trafficking by Acute Myelogenous Leukemia Exosomes

Jianya Huan, Noah I. Hornick, Matthew J. Shurtleff, +4

Cancer Research

Rna TraffickingMolecular BiologyExtracellular MicrovesiclesExosome-sized VesiclesBone Marrow +16

Serum Exosome MicroRNA as a Minimally-Invasive Early Biomarker of AML

Noah I. Hornick, Jianya Huan, Ben Doron, +4

Scientific Reports

Enhanced FoxP3 expression and Treg cell function in pregnant and estrogen-treated mice

Magdalena Polanczyk, Corwyn Hopke, Jianya Huan, +2

Journal of Neuroimmunology

Knockout MouseDevelopmental BiologyTreg Cell FunctionEstrogen-treated MiceHormonal Receptor +8

AML suppresses hematopoiesis by releasing exosomes that contain microRNAs targeting c-MYB

Noah I. Hornick, Ben Doron, Sherif Abdelhamed, +6

Science Signaling

ImmunologyPathologyAml ExosomesTumor BiologyMyeloid Neoplasia +16

Self-Enforcing Feedback Activation between BCL6 and Pre-B Cell Receptor Signaling Defines a Distinct Subtype of Acute Lymphoblastic Leukemia

Huimin Geng, Christian Hurtz, Kyle Lenz, +35

Cancer Cell

Hematological MalignancySignal TransductionMixed-phenotype Acute LeukemiaMalignant Blood DisorderHematology +8

Interferon-beta-1a treatment increases CD56bright natural killer cells and CD4+CD25+ Foxp3 expression in subjects with multiple sclerosis

Arthur A. Vandenbark, Jianya Huan, Marisa Agotsch, +5

Journal of Neuroimmunology

Cd4+cd25+ Foxp3 ExpressionAutoimmune DiseaseImmunologyImmune RegulationImmunologic Mechanism +8

Recombinant TCR Ligand Induces Tolerance to Myelin Oligodendrocyte Glycoprotein 35-55 Peptide and Reverses Clinical and Histological Signs of Chronic Experimental Autoimmune Encephalomyelitis in HLA-DR2 Transgenic Mice

Arthur A. Vandenbark, Cathleen Rich, Jeff Mooney, +7

The Journal of Immunology

ImmunologyImmune RegulationImmunologic MechanismImmunotherapyImmune Dysregulation +16

Therapeutic vaccination with a trivalent T‐cell receptor (TCR) peptide vaccine restores deficient <i>FoxP3</i> expression and TCR recognition in subjects with multiple sclerosis

Arthur A. Vandenbark, Nicole Culbertson, Richard M. Bartholomew, +12

Immunology

A Promising Therapeutic Approach for Multiple Sclerosis: Recombinant T-Cell Receptor Ligands Modulate Experimental Autoimmune Encephalomyelitis by Reducing Interleukin-17 Production and Inhibiting Migration of Encephalitogenic Cells into the CNS

Sushmita Sinha, Sandhya Subramanian, Thomas M. Proctor, +7

Journal of Neuroscience