Fangbin Han

Discovery of Biaryl Amides as Potent, Orally Bioavailable, and CNS Penetrant RORγt Inhibitors

Yonghui Wang, Wei Cai, Yaobang Cheng et al. · ACS Medicinal Chemistry Letters · 2015 · 76 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth

Chunyan Ren, Guangtao Zhang, Fangbin Han et al. · Proceedings of the National Academy of Sciences · 2018 · 68 citations · Full text

Medicine, Molecular Biology, Oncology +9

Discovery of a Novel Series of Thienopyrimidine as Highly Potent and Selective PI3K Inhibitors

Fangbin Han, Songwen Lin, Peng Liu et al. · ACS Medicinal Chemistry Letters · 2015 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

BRD4‐PRC2 represses transcription of T‐helper 2‐specific negative regulators during T‐cell differentiation

Li Zhao, Yiqi Wang, Anbalagan Jaganathan et al. · The EMBO Journal · 2023 · 21 citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Synthesis and structure–activity relationships of PI3K/mTOR dual inhibitors from a series of 2-amino-4-methylpyrido[2,3-d]pyrimidine derivatives

Fangbin Han, Songwen Lin, Peng Liu et al. · Bioorganic & Medicinal Chemistry Letters · 2014 · 18 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14