MCU-dependent mitochondrial Ca2+ inhibits NAD+/SIRT3/SOD2 pathway to promote ROS production and metastasis of HCC cells

Tingting Ren, H Zhang, J Wang, +9

Oncogene

Cancer ResearchMitochondrial FunctionHcc CellsCell BiologyReactive Oxygen Specie +7

Tumor Necrosis Factor-α– and Interleukin-1β–Dependent Matrix Metalloproteinase-3 Expression in Nucleus Pulposus Cells Requires Cooperative Signaling via Syndecan 4 and Mitogen-Activated Protein Kinase–NF-κB Axis

Xin Wang, Hua Wang, Hao Yang, +4

American Journal Of Pathology

Resistin promotes CCL4 expression through toll-like receptor-4 and activation of the p38-MAPK and NF-κB signaling pathways: implications for intervertebral disc degeneration

Zhonghai Li, X. Wang, Hongbo Pan, +7

Osteoarthritis and Cartilage

InflammationSignal TransductionCcl4 ExpressionSynaptic SignalingNf-κb Signaling Pathways +12

Low back pain associated with lumbar disc herniation: role of moderately degenerative disc and annulus fibrous tears.

Hao Yang, Hui Liu, Zemin Li, +4

PubMed

Intervertebral DiscPain MedicineSpinal DisorderOrthopaedic SurgeryLumbar Spine +18

Both expression of cytokines and posterior annulus fibrosus rupture are essential for pain behavior changes induced by degenerative intervertebral disc: An experimental study in rats

Zemin Li, Hui Liu, Hao Yang, +5

Journal of Orthopaedic Research®

Main thoracic curve adolescent idiopathic scoliosis: association of higher rod stiffness and concave-side pedicle screw density with improvement in sagittal thoracic kyphosis restoration

Hui Liu, Zemin Li, Sibei Li, +5

Journal of Neurosurgery Spine

A ROS‐Responsive Lipid Nanoparticles Release Multifunctional Hydrogel Based on Microenvironment Regulation Promotes Infected Diabetic Wound Healing

Hao Yang, Dongming Lv, Shanqiang Qu, +11

Advanced Science

LIM mineralization protein‐1 suppresses TNF‐α induced intervertebral disc degeneration by maintaining nucleus pulposus extracellular matrix production and inhibiting matrix metalloproteinases expression

Hui Liu, Hehai Pan, Hao Yang, +7

Journal of Orthopaedic Research®

Intervertebral DiscImmunologyImmune RegulationPathologyImbalanced Metabolism +18

Prolyl-4-hydroxylase Domain Protein 2 Controls NF-κB/p65 Transactivation and Enhances the Catabolic Effects of Inflammatory Cytokines on Cells of the Nucleus Pulposus

Jun Li, Y. Edward Wen, Shuai Jiang, +4

Journal of Biological Chemistry

ImmunologyImmune RegulationPathologyCellular PhysiologyPhd Isoforms +17

Secreted Factors From Intervertebral Disc Cells and Infiltrating Macrophages Promote Degenerated Intervertebral Disc Catabolism

Hao Yang, Bo Liu, Yajun Liu, +4

Spine