pMGF505-7R determines pathogenicity of African swine fever virus infection by inhibiting IL-1β and type I IFN production

Jiangnan Li, Jie Song, Li Kang, +10

PLoS Pathogens

Extraction and antioxidant activities of polysaccharides from roots of Arctium lappa L.

Yuanyuan Jiang, Jun Yu, Yabo Li, +4

International Journal of Biological Macromolecules

Antioxidant ActivitiesPolysaccharidePhytochemicalPhytochemistryMedicine +3

DDX19A Senses Viral RNA and Mediates NLRP3-Dependent Inflammasome Activation

Jiangnan Li, Liang Hu, Yuanyuan Liu, +4

The Journal of Immunology

Microbial PathogensInnate Immune SystemImmunologyImmune RegulationViral Pathogenesis +17

African Swine Fever Virus pI215L Negatively Regulates cGAS-STING Signaling Pathway through Recruiting RNF138 to Inhibit K63-Linked Ubiquitination of TBK1

Li Huang, Wenjie Xu, Hongyang Liu, +13

The Journal of Immunology

Secondary Haemophilus parasuis infection enhances highly pathogenic porcine reproductive and respiratory syndrome virus (HP-PRRSV) infection-mediated inflammatory responses

Jiangnan Li, Shengnan Wang, Changyao Li, +14

Veterinary Microbiology

Host ResponsePathogenesisImmunologyPathogenic Porcine ReproductiveRespiratory Infection +7

DDX19 Inhibits Type I Interferon Production by Disrupting TBK1-IKKε-IRF3 Interactions and Promoting TBK1 and IKKε Degradation

Kunli Zhang, Yuanfeng Zhang, Juan Xue, +14

Cell Reports

Ubiquitin-Conjugating Enzyme 2S Enhances Viral Replication by Inhibiting Type I IFN Production through Recruiting USP15 to Deubiquitinate TBK1

Li Huang, Hongyang Liu, Kunli Zhang, +12

Cell Reports

Viral ReplicationFamily MembersInnate Immune SystemImmunologyImmune Regulation +18

Encephalomyocarditis Virus 3C Protease Relieves TRAF Family Member-associated NF-κB Activator (TANK) Inhibitory Effect on TRAF6-mediated NF-κB Signaling through Cleavage of TANK

Li Huang, Qinfang Liu, Lijie Zhang, +17

Journal of Biological Chemistry

InflammationSignal TransductionCell SignalingReceptor Tyrosine KinaseImmunology +9

Encephalomyocarditis virus 3C protease attenuates type I interferon production through disrupting the TANK–TBK1–IKKε–IRF3 complex

Li Huang, Tao Xiong, Huibin Yu, +14

Biochemical Journal

Deletion of African Swine Fever Virus (ASFV) H240R Gene Attenuates the Virulence of ASFV by Enhancing NLRP3-Mediated Inflammatory Responses

Li Huang, Hongyang Liu, Guangqiang Ye, +15

Journal of Virology