Wenhan Lu

A genomic mutational constraint map using variation in 76,156 human genomes

Siwei Chen, Laurent C. Francioli, Julia K. Goodrich et al. · Nature · 2023 · 1.1K citations · Full text

Medicine, Genetics, Evolutionary Biology +8

Systematic single-variant and gene-based association testing of thousands of phenotypes in 394,841 UK Biobank exomes

Konrad J. Karczewski, Matthew Solomonson, Katherine R. Chao et al. · Cell Genomics · 2022 · 275 citations · Full text

Genome-wide Association Study, Genetic Analysis, Functional Genomics +13

Pan-UK Biobank GWAS improves discovery, analysis of genetic architecture, and resolution into ancestry-enriched effects

Konrad J. Karczewski, Rahul Gupta, Masahiro Kanai et al. · 2024 · 160 citations · Full text

Genetics, Genetic Epidemiology, Ancestry-enriched Effects +21

Systematic single-variant and gene-based association testing of thousands of phenotypes in 426,370 UK Biobank exomes

Konrad J. Karczewski, Matthew Solomonson, Katherine R. Chao et al. · 2021 · 62 citations · Full text

Rare Variation, Genetics, Genetic Epidemiology +20

Pan-UK Biobank genome-wide association analyses enhance discovery and resolution of ancestry-enriched effects

Konrad J. Karczewski, Rahul Gupta, Masahiro Kanai et al. · Nature Genetics · 2025 · 31 citations