Yansu Guo

Global CNS Transduction of Adult Mice by Intravenously Delivered rAAVrh.8 and rAAVrh.10 and Nonhuman Primates by rAAVrh.10

Bin Yang, Shaoyong Li, Hongyan Wang et al. · Molecular Therapy · 2014 · 204 citations · Full text

Trehalose decreases mutant SOD1 expression and alleviates motor deficiency in early but not end-stage amyotrophic lateral sclerosis in a SOD1-G93A mouse model

Y. Li, Yansu Guo, xinying wang et al. · Neuroscience · 2015 · 95 citations

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Molecular Neuroscience +8

Widespread spinal cord transduction by intrathecal injection of rAAV delivers efficacious RNAi therapy for amyotrophic lateral sclerosis

Hongyan Wang, Bin Yang, Linghua Qiu et al. · Human Molecular Genetics · 2013 · 88 citations · Full text

Intrathecal Injection, Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis +12

Mitochondrial dysfunction in human TDP-43 transfected NSC34 cell lines and the protective effect of dimethoxy curcumin

Lu Jinsheng, Weisong Duan, Yansu Guo et al. · Brain Research Bulletin · 2012 · 85 citations

Nsc34 Cell Lines, Mitochondrial Function, Biochemistry +9

Full-length TDP-43 and its C-terminal fragments activate mitophagy in NSC34 cell line

Kun Hong, Yi Li, Weisong Duan et al. · Neuroscience Letters · 2012 · 78 citations

Signal Transduction, Molecular Biology, Cellular Biology +7