M. Omar F. Khan

Use of an Additional Hydrophobic Binding Site, the Z Site, in the Rational Drug Design of a New Class of Stronger Trypanothione Reductase Inhibitor, Quaternary Alkylammonium Phenothiazines

M. Omar F. Khan, Susan E. Austin, Cecil Chan et al. · Journal of Medicinal Chemistry · 2000 · 115 citations · Full text

Bioorganic Chemistry, Lead Drug Structures, Antiparasitic Agent +18

Trypanothione reductase: a viable chemotherapeutic target for antitrypanosomal and antileishmanial drug design.

M. Omar F. Khan · PubMed · 2007 · 55 citations · Full text

Bioorganic Chemistry, Aldo-keto Reductase, Antiparasitic Agent +17

Trypanothione Reductase: A Viable Chemotherapeutic Target for Antitrypanosomal and Antileishmanial Drug Design

M. Omar F. Khan · Drug Target Insights · 2007 · 55 citations · Full text

In vitro anti-inflammatory activities of new steroidal antedrugs: [16α,17α-d] Isoxazoline and [16α,17α-d]-3′-hydroxy-iminoformyl isoxazoline derivatives of prednisolone and 9α-fluoroprednisolone

Kwan-K. Park, Dong-H. Ko, Zhengqing You et al. · Steroids · 2005 · 35 citations

Inflammation, Medicinal Chemistry, Anti-inflammatory +10

Rational drug design using trypanothione reductase as a target for anti-trypanosomal and anti-leishmanial drug leads.

Susan E. Austin, M. Omar F. Khan, Kenneth T. Douglas · PubMed · 1999 · 23 citations

Bioorganic Chemistry, Antiparasitic Agent, Pharmacotherapy +16