Bazedoxifene as a Novel GP130 Inhibitor for Pancreatic Cancer Therapy

Xiaojuan Wu, Yang Cao, Hui Xiao, +2

Molecular Cancer Therapeutics

Surgical OncologyChemoprevention StrategyPharmacotherapyCancer BiologyTumor Biology +18

Enhanced IL-6/phosphorylated STAT3 signaling is related to the imbalance of circulating T follicular helper/T follicular regulatory cells in patients with rheumatoid arthritis

Qian Niu, Zhuochun Huang, Xiaojuan Wu, +6

Arthritis Research & Therapy

Bazedoxifene is a novel IL-6/GP130 inhibitor for treating triple-negative breast cancer

Jilai Tian, Xiang Chen, Shengling Fu, +9

Breast Cancer Research and Treatment

Breast OncologyOncologyMedicineBreast CancerPharmacotherapy +5

GTSE1 promotes cell migration and invasion by regulating EMT in hepatocellular carcinoma and is associated with poor prognosis

Xiaojuan Wu, Hongbo Wang, Yifan Lian, +7

Scientific Reports

A Novel Small Molecular STAT3 Inhibitor, LY5, Inhibits Cell Viability, Cell Migration, and Angiogenesis in Medulloblastoma Cells

Hui Xiao, Hemant K. Bid, David Jou, +5

Journal of Biological Chemistry

Rapamycin upregulates glutamate transporter and IL-6 expression in astrocytes in a mouse model of Parkinson’s disease

Yunlong Zhang, Xiaoliang He, Xiaojuan Wu, +7

Cell Death and Disease

Intestinal proinflammatory macrophages induce a phenotypic switch in interstitial cells of Cajal

Xuyong Chen, Xinyao Meng, Hongyi Zhang, +14

Journal of Clinical Investigation

Repositioning Bazedoxifene as a novel IL-6/GP130 signaling antagonist for human rhabdomyosarcoma therapy

Hui Xiao, Hemant K. Bid, Xiang Chen, +7

PLoS ONE

Tumor BiologyChemoprevention StrategyMedicineHuman Rhabdomyosarcoma TherapyImmunology +10

Aspartate transaminase to platelet ratio index and gamma‐glutamyl transpeptidase‐to‐platelet ratio outweigh fibrosis index based on four factors and red cell distribution width‐platelet ratio in diagnosing liver fibrosis and inflammation in chronic hepatitis B

Xiaojuan Wu, Bei Cai, Zhenzhen Su, +4

Journal of Clinical Laboratory Analysis

Increased circulating Tfh to Tfr ratio in chronic renal allograft dysfunction: a pilot study

Lin Yan, Yamei Li, Yi Li, +5

BMC Immunology