Brazilein, an important immunosuppressive component from Caesalpinia sappan L.

Min Ye, Weidong Xie, Lei Fan, +4

International Immunopharmacology

PhytopharmacologyMicrobiologyCaesalpinia Sappan LBotany

Rapamycin Eye Drops Suppress Lacrimal Gland Inflammation In a Murine Model of Sjögren's Syndrome

Mihir Shah, Maria C. Edman, Srikanth Reddy Janga, +11

Investigative Ophthalmology & Visual Science

Increased Cathepsin S activity associated with decreased protease inhibitory capacity contributes to altered tear proteins in Sjögren’s Syndrome patients

Maria C. Edman, Srikanth Reddy Janga, Zhen Meng, +16

Scientific Reports

Delivery of Bone Marrow-Derived Mesenchymal Stem Cells Improves Tear Production in a Mouse Model of Sjögren’s Syndrome

Hema Aluri, Mahta Samizadeh, Maria C. Edman, +9

Stem Cells International

A new tactic to treat postprandial hyperlipidemia in diabetic rats with gastroparesis by improving gastrointestinal transit

Weidong Xie, Dongming Xing, Yunan Zhao, +4

European Journal of Pharmacology

Metabolic SyndromeMedicinePostprandial HyperlipidemiaPhysiologyDiabetes +7

Toxicokinetics and internal exposure of acrylamide: new insight into comprehensively profiling mercapturic acid metabolites as short-term biomarkers in rats and Chinese adolescents

Qiao Wang, Xinyu Chen, Yiping Ren, +7

Archives of Toxicology

BiochemistryMedicineToxicologyToxicological AspectEnvironmental Toxicology +9

Imbalanced Rab3D versus Rab27 increases cathepsin S secretion from lacrimal acini in a mouse model of Sjögren's Syndrome

Zhen Meng, Maria C. Edman, Pang‐Yu Hsueh, +5

American Journal of Physiology-Cell Physiology

SclerostinImmunologyImmune RegulationCathepsin S SecretionLacrimal Acini +17

Interferon-γ treatment in vitro elicits some of the changes in cathepsin S and antigen presentation characteristic of lacrimal glands and corneas from the NOD mouse model of Sjögren’s Syndrome

Zhen Meng, Wannita Klinngam, Maria C. Edman, +1

PLoS ONE

Laboratory ImmunologyImmunodeficienciesImmunologyImmune RegulationInnate Immunity +24

Longitudinal analysis of tear cathepsin S activity levels in male non-obese diabetic mice suggests its potential as an early stage biomarker of Sjögren’s Syndrome

Srikanth Reddy Janga, Mihir Shah, Yaping Ju, +3

Biomarkers

Analytical method development for α-amanitin and β-amanitin in plasma at ultra-trace level by online solid phase extraction-high performance liquid chromatography-triple quadrupole mass spectrometry and its application in poisoning events

Xiaomin Xu, Zhen Meng, Jingshun Zhang, +2

Journal of Pharmaceutical and Biomedical Analysis

Analytical Method DevelopmentAnalytical InstrumentationBiochemistryGas ChromatographyMedicine +10