Heterogeneity of Human Macrophages in Culture and in Atherosclerotic Plaques

Stephen W. Waldo, Yifu Li, Chiara Buono, +4

American Journal Of Pathology

InflammationVascular DiseaseHuman MacrophagesImmunologyPathology +7

Characterization of CCX282-B, an Orally Bioavailable Antagonist of the CCR9 Chemokine Receptor, for Treatment of Inflammatory Bowel Disease

Matthew J. Walters, Yu Wang, Trageen Baumgart, +13

Journal of Pharmacology and Experimental Therapeutics

CCR2 antagonist CCX140-B provides renal and glycemic benefits in diabetic transgenic human CCR2 knockin mice

Timothy J. Sullivan, Zhenhua Miao, Daniel J. Dairaghi, +17

American Journal of Physiology-Renal Physiology

Receptor 2ImmunologyInsulin SignalingInflammationMetabolic Syndrome +16

Constitutive Receptor-independent Low Density Lipoprotein Uptake and Cholesterol Accumulation by Macrophages Differentiated from Human Monocytes with Macrophage-Colony-stimulating Factor (M-CSF)

Bin Zhao, Yifu Li, Chiara Buono, +4

Journal of Biological Chemistry

ImmunologyHyperlipidemiaMacrophages DifferentiatedInflammationMacrophage-colony-stimulating Factor +14

Experimental evidence for the use of CCR2 antagonists in the treatment of type 2 diabetes

Timothy J. Sullivan, Zhenhua Miao, Bin Zhao, +11

Metabolism

Metabolic SyndromeDiabetes ManagementExperimental EvidenceCardiovascular DiseaseMedicine +8

Identification of a novel intracellular cholesteryl ester hydrolase (carboxylesterase 3) in human macrophages: compensatory increase in its expression after carboxylesterase 1 silencing

Bin Zhao, Jinghua Bie, Jing Wang, +2

American Journal of Physiology-Cell Physiology

Free CholesterolImmunologyImmunotherapyInflammationAutophagy +14

CCR2-Mediated Uptake of Constitutively Produced CCL2: A Mechanism for Regulating Chemokine Levels in the Blood

Bin Zhao, James J. Campbell, Catherina L. Salanga, +13

The Journal of Immunology

Endothelial cells injured by oxidized low density lipoprotein

Bin Zhao, Yuang Zhang, B. Liu, +2

American Journal of Hematology

Influence of low density lipoproteins on cytosolic free Ca2+ concentration and dense tubular system in human platelets

Bin Zhao, R. Dierichs, J.F. Liu, +3

Thrombosis Research

ThrombopoiesisThrombosisHuman PlateletsBlood PlateletTubular System +10

CCR2 antagonism leads to marked reduction in proteinuria and glomerular injury in murine models of focal segmental glomerulosclerosis (FSGS)

Zhenhua Miao, Linda Ertl, Dale Newland, +15

PLoS ONE

Glomerular DiseaseTherapeutic BenefitRenal PathologyImmunologyPathology +21