Yi Cui

A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria

Margaret A. Phillips, Julie Lotharius, Kennan C. Marsh et al. · Science Translational Medicine · 2015 · 375 citations

Medicine, Pharmacology, Pharmacotherapy +9

Simulation of multiple ion channel block provides improved early prediction of compounds’ clinical torsadogenic risk

Gary R. Mirams, Yi Cui, Anna Sher et al. · Cardiovascular Research · 2011 · 334 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

Comparison of Electrophysiological Data From Human-Induced Pluripotent Stem Cell–Derived Cardiomyocytes to Functional Preclinical Safety Assays

Kate Harris, Mike Aylott, Yi Cui et al. · Toxicological Sciences · 2013 · 227 citations · Full text

Medicine, Cardiology, Pharmacology +16

Prediction of Thorough QT study results using action potential simulations based on ion channel screens

Gary R. Mirams, Mark Davies, Stephen Brough et al. · Journal of Pharmacological and Toxicological Methods · 2014 · 96 citations · Full text

Medicine, Cardiology, Pharmacology +17

Variability in high-throughput ion-channel screening data and consequences for cardiac safety assessment

Ryan C. Elkins, Mark Davies, Stephen Brough et al. · Journal of Pharmacological and Toxicological Methods · 2013 · 94 citations · Full text

Medicine, Cardiology, Pharmacology +17