Krzysztof M. Żak

Structure of the Complex of Human Programmed Death 1, PD-1, and Its Ligand PD-L1

Krzysztof M. Żak, Radosław Kitel, Sara Przetocka et al. · Structure · 2015 · 526 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +13

Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1)

Krzysztof M. Żak, P. Grudnik, Katarzyna Guzik et al. · Oncotarget · 2016 · 423 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +17

Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Death-Ligand 1 (PD-1/PD-L1) Interaction via Transiently Induced Protein States and Dimerization of PD-L1

Katarzyna Guzik, Krzysztof M. Żak, P. Grudnik et al. · Journal of Medicinal Chemistry · 2017 · 360 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17

Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells

Łukasz Skalniak, Krzysztof M. Żak, Katarzyna Guzik et al. · Oncotarget · 2017 · 311 citations · Full text

Life Sciences, Immunology, Pharmacology +16

Bioactive Macrocyclic Inhibitors of the PD‐1/PD‐L1 Immune Checkpoint

Katarzyna Magiera‐Mularz, Łukasz Skalniak, Krzysztof M. Żak et al. · Angewandte Chemie International Edition · 2017 · 185 citations · Full text

Medicine, Medicinal Chemistry, Oncology +17