Yoshiaki Kawashimà

Preparations of biodegradable nanospheres of water-soluble and insoluble drugs with D,L-lactide/glycolide copolymer by a novel spontaneous emulsification solvent diffusion method, and the drug release behavior

Toshiyuki Niwa, Hirofumi Takeuchi, Tomoya Hino et al. · Journal of Controlled Release · 1993 · 483 citations · Full text

Pharmacy, Pharmaceutics, Pharmacokinetics +17

Preparation of poly(dl-lactide-co-glycolide) nanoparticles by modified spontaneous emulsification solvent diffusion method

Hideki Murakami, Masao Kobayashi, Hirofumi Takeuchi et al. · International Journal of Pharmaceutics · 1999 · 398 citations · Full text

Pharmacy, Materials Engineering, Materials Science +12

Biodegradable nanoparticles loaded with insulin–phospholipid complex for oral delivery: Preparation, in vitro characterization and in vivo evaluation

Fude Cui, Kai Shi, Liqiang Zhang et al. · Journal of Controlled Release · 2006 · 389 citations

Pharmacy, Pharmaceutics, Pharmacology +17

Enteral Absorption of Insulin in Rats from Mucoadhesive Chitosan-Coated Liposomes

Hirofumi Takeuchi, Hiromitsu Yamamoto, Toshiyuki Niwa et al. · Pharmaceutical Research · 1996 · 388 citations · Full text

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +14

Surface-modified PLGA nanosphere with chitosan improved pulmonary delivery of calcitonin by mucoadhesion and opening of the intercellular tight junctions

Hiromitsu Yamamoto, Yoshio Kuno, Shohei Sugimoto et al. · Journal of Controlled Release · 2004 · 387 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +16