Xiaojing Yuan

NO hyperpolarizes pulmonary artery smooth muscle cells and decreases the intracellular Ca2+ concentration by activating voltage-gated K+ channels.

Xiaojing Yuan, M. Tod, Lewis J. Rubin et al. · Proceedings of the National Academy of Sciences · 1996 · 153 citations · Full text

Pulmonary Hypertension, Cellular Physiology, Molecular Pharmacology +22

In Silico Screening-Based Discovery of Novel Inhibitors of Human Cyclic GMP–AMP Synthase: A Cross-Validation Study of Molecular Docking and Experimental Testing

Wenfeng Zhao, Muya Xiong, Xiaojing Yuan et al. · Journal of Chemical Information and Modeling · 2020 · 66 citations

Structural basis for ligand recognition of the human thromboxane A2 receptor

Hengxin Fan, Shuanghong Chen, Xiaojing Yuan et al. · Nature Chemical Biology · 2018 · 65 citations

Signal Transduction, Biochemistry, G Protein-coupled Receptor +12

The Molecular Mechanism Underlying Ligand Binding to the Membrane-Embedded Site of a G-Protein-Coupled Receptor

Xiaojing Yuan, Stefano Raniolo, Vittorio Limongelli et al. · Journal of Chemical Theory and Computation · 2018 · 49 citations

Discovery of a Novel Series of Imidazo[1,2-<i>a</i>]pyrimidine Derivatives as Potent and Orally Bioavailable Lipoprotein-Associated Phospholipase A₂ Inhibitors

Xinde Chen, Wenwei Xu, Kai Wang et al. · Journal of Medicinal Chemistry · 2015 · 41 citations · Full text

Lipoprotein-associated Phospholipase A2, Molecular Pharmacology, Medicinal Chemistry +14