Enhanced neuroinflammation mediated by DNA methylation of the glucocorticoid receptor triggers cognitive dysfunction after sevoflurane anesthesia in adult rats subjected to maternal separation during the neonatal period

Yangzi Zhu, Yu Wang, Rui Yao, +5

Journal of Neuroinflammation

Ketamine Affects the Neurogenesis of the Hippocampal Dentate Gyrus in 7-Day-Old Rats

He Huang, Cunming Liu, Jie Sun, +4

Neurotoxicity Research

Synaptic PlasticityNeurophysiologyNeuroanatomyMedicineNeurotransmitter +11

High mobility group box-1 mediates hippocampal inflammation and contributes to cognitive deficits in high-fat high-fructose diet-induced obese rats

Min Yu, He Huang, Shiyang Dong, +3

Brain Behavior and Immunity

ObesityMetabolic SyndromeEnergy HomeostasisMedicinePhysiology +4

Impaired synaptic plasticity and decreased glutamatergic neuron excitability induced by SIRT1/BDNF downregulation in the hippocampal CA1 region are involved in postoperative cognitive dysfunction

Wei-Feng Wu, Chen Chen, Jia-Tao Lin, +12

Cellular & Molecular Biology Letters

Ketamine Interferes with the Proliferation and Differentiation of Neural Stem Cells in the Subventricular Zone of Neonatal Rats

He Huang, Lu Liu, Bing Li, +5

Cellular Physiology and Biochemistry

Ketamine Inhibits Proliferation of Neural Stem Cell from Neonatal Rat Hippocampus<b><i>in Vitro</i></b>

Yuqing Wu, Tuo Liang, He Huang, +8

Cellular Physiology and Biochemistry

Neonatal Anesthesia by Ketamine in Neonatal Rats Inhibits the Proliferation and Differentiation of Hippocampal Neural Stem Cells and Decreases Neurocognitive Function in Adulthood via Inhibition of the Notch1 Signaling Pathway

He Huang, Chao Zhao, Hu Qian, +6

Molecular Neurobiology

Developmental BiologyDissociative PharmacologyDevelopmental Cognitive NeuroscienceNeurophysiologyNeonatal Anesthesia +12

Early Serum Metabolism Profile of Post-operative Delirium in Elderly Patients Following Cardiac Surgery With Cardiopulmonary Bypass

He Huang, Jingjing Han, Yan Li, +4

Frontiers in Aging Neuroscience

Repeated 2% sevoflurane administration in 7‑ and 60-day-old rats

He Huang, Cunming Liu, Jie Sun, +3

Der Anaesthesist

MedicineNeuropharmacologyToxicologyPharmacotherapy60-Day-old Rats +6

Neuroprotective Effects of Dexmedetomidine on the Ketamine-Induced Disruption of the Proliferation and Differentiation of Developing Neural Stem Cells in the Subventricular Zone

Huanhuan Sha, Peipei Peng, Guohua Wei, +3

Frontiers in Pediatrics