Thomas J. Payne

Beyond the Endosomal Bottleneck: Understanding the Efficiency of mRNA/LNP Delivery

Haiyin Liu, Moore Chen, Thomas J. Payne et al. · Advanced Functional Materials · 2024 · 66 citations · Full text

Pharmacy, Molecular Biology, Pharmaceutics +17

Tailored Monoacyl Poly(2-oxazoline)- and Poly(2-oxazine)-Lipids as PEG-Lipid Alternatives for Stabilization and Delivery of mRNA-Lipid Nanoparticles

He Xie, Thomas J. Payne, Asuka Takanashi et al. · Biomacromolecules · 2024 · 36 citations

Pharmacy, Immunology, Pharmaceutics +17

A versatile antibody capture system drives specific in vivo delivery of mRNA-loaded lipid nanoparticles

Moore Chen, Daniel Yuen, Victoria M. McLeod et al. · Nature Nanotechnology · 2025 · 35 citations · Full text

Pharmacy, Biotechnology, Pharmaceutics +17

Impact of ionizable lipid type on the pharmacokinetics and biodistribution of mRNA-lipid nanoparticles after intravenous and subcutaneous injection

Yuxiang Ren, Lihuan Lin, Mohammad Abdallah et al. · Journal of Controlled Release · 2025 · 34 citations · Full text

Pharmacy, Pharmaceutics, Pharmacokinetics +17

Efficient mRNA delivery to resting T cells to reverse HIV latency

Paula M. Cevaal, Stanislav Kan, Michael A. Moso et al. · Nature Communications · 2025 · 29 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +17