Breast cancer exosomes contribute to pre-metastatic niche formation and promote bone metastasis of tumor cells

Xinxin Yuan, Niansong Qian, Shukuan Ling, +25

Theranostics

Ceramide-Initiated Protein Phosphatase 2A Activation Contributes to Arterial Dysfunction In Vivo

Leena P. Bharath, Ting Ruan, Youyou Li, +18

Diabetes

Vascular DiseaseOxidative StressThrombosisMetabolic SyndromeCeramide Accumulation +17

Targeting E3 Ubiquitin Ligase WWP1 Prevents Cardiac Hypertrophy Through Destabilizing DVL2 via Inhibition of K27-Linked Ubiquitination

Dingsheng Zhao, Guohui Zhong, Jianwei Li, +24

Circulation

The mechanosensitive lncRNA Neat1 promotes osteoblast function through paraspeckle-dependent Smurf1 mRNA retention

Caizhi Liu, Xingcheng Gao, Yuheng Li, +22

Bone Research

Exercise improves the dilatation function of mesenteric arteries in postmyocardial infarction rats via a PI3K/Akt/eNOS pathway-mediated mechanism

Youhua Wang, Shengpeng Wang, W. Gil Wier, +12

American Journal of Physiology-Heart and Circulatory Physiology

Heart FailurePeripheral ResistanceCardiovascular FunctionKinesiologyExercise +18

Swimming Exercise Alleviates Endothelial Mitochondrial Fragmentation via Inhibiting Dynamin-Related Protein-1 to Improve Vascular Function in Hypertension

Guohua Li, Ke Xu, Wenjuan Xing, +10

Hypertension

A Novel Mechanism for Vascular Insulin Resistance in Normotensive Young SHRs

Wenjuan Xing, Wenjun Yan, Peilin Liu, +6

Hypertension

HypertensionVascular Insulin ResistanceInsulin SignalingNormotensive Young ShrsMetabolic Syndrome +21

Improvement of vascular insulin sensitivity by downregulation of GRK2 mediates exercise-induced alleviation of hypertension in spontaneously hypertensive rats

Wenjuan Xing, Youyou Li, Haifeng Zhang, +4

American Journal of Physiology-Heart and Circulatory Physiology

HypertensionPhysical ActivityCardiovascular FunctionExercise-induced AlleviationInsulin Signaling +20

Decoding ceRNA regulatory network and autophagy-related genes in benign prostatic hyperplasia

Liang Zhou, Youyou Li, Jiaren Li, +4

International Journal of Biological Macromolecules

Systems BiologyFunctional GenomicsAutophagy-related GenesGeneticsAutophagy +9

Aerobic Exercise Inhibits Sympathetic Nerve Sprouting and Restores β-Adrenergic Receptor Balance in Rats with Myocardial Infarction

Ting Chen, Mengxin Cai, Youyou Li, +7

PLoS ONE