DPPC-cholesterol phase diagram using coarse-grained Molecular Dynamics simulations

Wang Yin, Paraskevi Gkeka, Julian E. Fuchs, +2

Biochimica et Biophysica Acta (BBA) - Biomembranes

EngineeringDppc-cholesterol Phase DiagramComputational ChemistryLipid MovementMolecular Dynamics +1

Aspirin-loaded nanoexosomes as cancer therapeutics

Phuong H.L. Tran, Tao Wang, Wang Yin, +4

International Journal of Pharmaceutics

Aspirin-loaded NanoexosomesNanomedicinePharmaceutical NanotechnologyNano-drug DeliveryTumor Targeting +1

Transforming doxorubicin into a cancer stem cell killer via EpCAM aptamer-mediated delivery

Dongxi Xiang, Sarah Shigdar, Andrew G. D. Bean, +16

Theranostics

ImmunologyCsc-targeting Epcam AptamerCancer StemTumor BiologyDrug Resistance +17

Blood TfR+ exosomes separated by a pH-responsive method deliver chemotherapeutics for tumor therapy

Lijun Yang, Donglin Han, Qi Zhan, +14

Theranostics

The inhibition of ABCB1/MDR1 or ABCG2/BCRP enables doxorubicin to eliminate liver cancer stem cells

Wang Yin, Dongxi Xiang, Tao Wang, +10

Scientific Reports

In silico design and validation of high-affinity RNA aptamers targeting epithelial cellular adhesion molecule dimers

David R. Bell, Jeffrey K. Weber, Wang Yin, +2

Proceedings of the National Academy of Sciences

Development of a nanoamorphous exosomal delivery system as an effective biological platform for improved encapsulation of hydrophobic drugs

Phuong H.L. Tran, Tao Wang, Wang Yin, +7

International Journal of Pharmaceutics

Cell-based Drug DeliveryNanomedicineImproved EncapsulationEngineeringDrug Delivery Systems +6

Aptamer-mediated survivin RNAi enables 5-fluorouracil to eliminate colorectal cancer stem cells

Hadi AlShamaileh, Tao Wang, Dongxi Xiang, +11

Scientific Reports

Pyrroloquinoline quinone ameliorates renal fibrosis in diabetic nephropathy by inhibiting the pyroptosis pathway in C57BL/6 mice and human kidney 2 cells

Xuefeng Qu, Bingzhong Zhai, Yifeng Liu, +11

Biomedicine & Pharmacotherapy

A Detailed Protein-SELEX Protocol Allowing Visual Assessments of Individual Steps for a High Success Rate

Tao Wang, Wang Yin, Hadi AlShamaileh, +12

Human Gene Therapy Methods

Exponential EnrichmentMolecular BiologyNucleic Acid BiomarkersBait ProteinAntibody Engineering +20