You Wu

A PAM-free CRISPR/Cas12a ultra-specific activation mode based on toehold-mediated strand displacement and branch migration

You Wu, Wang Luo, Zhi Weng et al. · Nucleic Acids Research · 2022 · 77 citations · Full text

Engineering, Molecular Biology, Crispr Activation Modes +18

CD36 Promotes Podocyte Apoptosis by Activating the Pyrin Domain-Containing-3 (NLRP3) Inflammasome in Primary Nephrotic Syndrome

Xuejun Yang, You Wu, Qianqian Li et al. · Medical Science Monitor · 2018 · 38 citations · Full text

Primary Nephrotic Syndrome, Apoptosis, Immunology +21

Unmodificated stepless regulation of CRISPR/Cas12a multi-performance

Rong Zhao, Wang Luo, You Wu et al. · Nucleic Acids Research · 2023 · 33 citations · Full text

Off-target Effect, Engineering, Crispr/cas12a Regulation Strategy +12

A novel fluorescence biosensor based on double-stranded DNA branch migration-induced HCR and DNAzyme feedback circuit for sensitive detection of Pseudomonas aeruginosa (clean version)

Yaxing Xie, Guoming Xie, Jinshan Yuan et al. · Analytica Chimica Acta · 2022 · 27 citations

Novel Fluorescence Biosensor, Pathogen Detection, Nucleic Acid Amplification +6

Proximity ligation assay mediated rolling circle amplification strategy for in situ amplified imaging of glycosylated PD-L1

Yixin Fu, Husun Qian, Xi Zhou et al. · Analytical and Bioanalytical Chemistry · 2021 · 21 citations

Proximity Ligation, Biochemistry, Novel Imaging Method +11