Haematopoietic stem and progenitor cells from human pluripotent stem cells

Ryohichi Sugimura, Deepak Kumar Jha, Areum Han, +16

Nature

Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma

John T. Powers, Kaloyan M. Tsanov, Daniel S. Pearson, +17

Nature

Multiple MechanismsSmall RnaMicrorna DetectionMedicineCell Biology +2

The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation

Qin Li, Sika Zheng, Areum Han, +4

eLife

Brain DevelopmentGeneticsAdult Protein IsoformsNeurodevelopmentSplicing Variant +20

Sam68 Regulates a Set of Alternatively Spliced Exons during Neurogenesis

Geetanjali Chawla, Chia-Ho Lin, Areum Han, +3

Molecular and Cellular Biology

YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow

Vanessa Lundin, Wade W. Sugden, Lindsay N. Theodore, +9

Developmental Cell

MechanobiologyBiomechanical ForcesMedicineStem Cell MobilizationPhysiology +10

MADS: A new and improved method for analysis of differential alternative splicing by exon-tiling microarrays

Yi Xing, Peter Stoilov, Karen Kapur, +5

RNA

Improved MethodGeneticsMolecular BiologyGenomicsGene Expression Profiling +17

Regulation of embryonic haematopoietic multipotency by EZH1

Linda T. Vo, Melissa A. Kinney, Xin Liu, +12

Nature

Cell LineageDevelopmental BiologyCell DivisionMorphogenesisEmbryonic Haematopoietic Multipotency +4

De Novo Prediction of PTBP1 Binding and Splicing Targets Reveals Unexpected Features of Its RNA Recognition and Function

Areum Han, Peter Stoilov, Anthony J. Linares, +3

PLoS Computational Biology

EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity

Ran Jing, Irene Scarfo, Mohamad Najia, +11

Cell stem cell

ImmunologyEzh1 RepressionCellular Immune ResponseAdult T-cell Leukemia-lymphomaImmunotherapy +4

LIN28 phosphorylation by MAPK/ERK couples signalling to the post-transcriptional control of pluripotency

Kaloyan M. Tsanov, Daniel S. Pearson, Zhaoting Wu, +9

Nature Cell Biology

Transcriptional RegulationSystems BiologySignal TransductionMapk/erk CouplesSignaling Pathway +8