Localized TRPA1 channel Ca ²⁺ signals stimulated by reactive oxygen species promote cerebral artery dilation

Michelle N. Sullivan, Albert L. Gonzales, Paulo W. Pires, +9

Science Signaling

Brain CirculationReactive Oxygen SpeciesCellular PhysiologySocial SciencesCerebral Vascular Regulation +18

Altered Inflammatory Response Is Associated With an Impaired Autonomic Input to the Bone Marrow in the Spontaneously Hypertensive Rat

Jasenka Zubcevic, Joo Yun Jun, Seungbum Kim, +12

Hypertension

Altered Inflammatory ResponseHypertensionImmunologyInflammationExaggerated Inflammation +16

Brain-Targeted (Pro)renin Receptor Knockdown Attenuates Angiotensin II–Dependent Hypertension

Wencheng Li, Hua Peng, Theresa Cao, +5

Hypertension

Intracerebroventricular Infusion of the (Pro)renin Receptor Antagonist PRO20 Attenuates Deoxycorticosterone Acetate-Salt–Induced Hypertension

Wencheng Li, Michelle Sullivan, Sheng Zhang, +4

Hypertension

Neuron-Specific (Pro)renin Receptor Knockout Prevents the Development of Salt-Sensitive Hypertension

Wencheng Li, Hua Peng, Eamonn P. Mehaffey, +8

Hypertension

Small molecule splicing modifiers with systemic HTT-lowering activity

Anuradha Bhattacharyya, Christopher R. Trotta, Jana Narasimhan, +21

Nature Communications

Transcriptional RegulationSystems BiologyNeurodegenerative DiseasesBroad DistributionNatural Sciences +13

(Pro)renin Receptor Mediates Both Angiotensin II-Dependent and -Independent Oxidative Stress in Neuronal Cells

Hua Peng, Wencheng Li, Dale M. Seth, +3

PLoS ONE

HypertensionCellular PhysiologyOxidative StressInflammationMolecular Pharmacology +19

CNS Inflammation and Bone Marrow Neuropathy in Type 1 Diabetes

Ping Hu, Jeffrey S. Thinschmidt, Yuanqing Yan, +17

American Journal Of Pathology

The Prorenin and (Pro)renin Receptor: New Players in the Brain Renin-Angiotensin System?

Wencheng Li, Hua Peng, Dale M. Seth, +1

International Journal of Hypertension

HypertensionNew PlayersSocial SciencesBrain PrrAdrenal Gland +20

(Pro)renin receptor knockdown in the paraventricular nucleus of the hypothalamus attenuates hypertension development and AT₁ receptor-mediated calcium events

Lucas A. C. Souza, Caleb J. Worker, Wencheng Li, +7

American Journal of Physiology-Heart and Circulatory Physiology