Celastrol-Induced Nur77 Interaction with TRAF2 Alleviates Inflammation by Promoting Mitochondrial Ubiquitination and Autophagy

Mengjie Hu, Qiang Luo, Gulimiran Alitongbieke, +20

Molecular Cell

InflammationCell AutophagyMitophagySignal TransductionMitochondrial Function +10

Histone Deacetylase 3 Couples Mitochondria to Drive IL-1β-Dependent Inflammation by Configuring Fatty Acid Oxidation

Zhexu Chi, Sheng Chen, Ting Xu, +16

Molecular Cell

InflammationChromatinHistone Deacetylase 3BiochemistryCouples Mitochondria +10

Epithelial Gasdermin D shapes the host-microbial interface by driving mucus layer formation

Jian Zhang, Qianzhou Yu, Danlu Jiang, +15

Science Immunology

Anthrax Lethal Toxin Has Direct and Potent Inhibitory Effects on B Cell Proliferation and Immunoglobulin Production

Hui Fang, Lixin Xu, Trina Y. Chen, +2

The Journal of Immunology

Humoral ResponseImmunologyCell DeathAnthrax LtImmunologic Mechanism +16

Anthrax Lethal Toxin Rapidly Activates Caspase-1/ICE and Induces Extracellular Release of Interleukin (IL)-1β and IL-18

Ruth Cordoba-Rodriguez, Hui Fang, Carla S. R. Lankford, +1

Journal of Biological Chemistry

Anthrax Lethal Toxin Blocks MAPK Kinase-Dependent IL-2 Production in CD4+ T Cells

Hui Fang, Ruth Cordoba-Rodriguez, Carla S. R. Lankford, +1

The Journal of Immunology

Ubiquitination of NLRP3 by gp78/Insig-1 restrains NLRP3 inflammasome activation

Ting Xu, Weiwei Yu, Hui Fang, +13

Cell Death and Differentiation

InflammationSignal TransductionSignaling PathwayImmunologyMolecular Biology +3

Kir2.1-mediated membrane potential promotes nutrient acquisition and inflammation through regulation of nutrient transporters

Weiwei Yu, Zhen Wang, Xiafei Yu, +18

Nature Communications

Glycosylation end products mediate damage and apoptosis of periodontal ligament stem cells induced by the JNK-mitochondrial pathway

Hui Fang, Kun Yang, Ping Tao Tang, +4

Aging

AKT controls NLRP3 inflammasome activation by inducing DDX3X phosphorylation

Xingchen Guo, Sheng Chen, Weiwei Yu, +15

FEBS Letters