Calpain-catalyzed cleavage and subcellular relocation of protein phosphotyrosine phosphatase 1B (PTP-1B) in human platelets.

John V. Frangioni, A. Oda, M. Smith, +2

The EMBO Journal

Calpain-catalyzed CleavageHuman PlateletsSignal TransductionProtein FunctionBiochemistry +9

Measurement of ionized calcium in blood platelets with the photoprotein aequorin. Comparison with Quin 2.

Peter C. Johnson, J. Anthony Ware, Paul Cliveden, +3

Journal of Biological Chemistry

Aequorin LoadingBiomedical EngineeringPhotoprotein AequorinThrombosisEnzyme Thrombin +17

pp60src is an endogenous substrate for calpain in human blood platelets

A. Oda, Brian Druker, Hideo Ariyoshi, +2

Journal of Biological Chemistry

Platelet CalpainMonoclonal Antibody 327Cellular PhysiologyHuman Blood PlateletsEndogenous Substrate +23

Effect of common agonists on cytoplasmic ionized calcium concentration in platelets. Measurement with 2-methyl-6-methoxy 8-nitroquinoline (quin2) and aequorin.

J. Anthony Ware, Peter C. Johnson, M. Smith, +1

Journal of Clinical Investigation

ThrombopoiesisMolecular PharmacologyThrombosisSignal TransductionBiochemistry +13

Hyperpermeability and ATP depletion induced by chronic hypoxia or glycolytic inhibition in Caco-2BBe monolayers

Naoki Unno, Michael J. Menconi, Andrew L. Salzman, +5

American Journal of Physiology-Gastrointestinal and Liver Physiology

Caco-2bbe MonolayersCytoskeletonMetabolic RemodelingRedox BiologyCellular Physiology +20

Association of pp60src with Triton X-100-insoluble residue in human blood platelets requires platelet aggregation and actin polymerization.

A. Oda, Brian Druker, M. Smith, +1

Journal of Biological Chemistry

Synergism of platelet-aggregating agents. Role of elevation of cytoplasmic calcium.

J. Anthony Ware, M. Smith, Salzman Ew

Journal of Clinical Investigation

Platelet-aggregating AgentsImmunologyCytoskeletonPharmacotherapyCellular Physiology +18

Hyperpermeability of intestinal epithelial monolayers is induced by NO: effect of low extracellular pH

Naoki Unno, Michael J. Menconi, M. Smith, +2

American Journal of Physiology-Gastrointestinal and Liver Physiology

Nitric OxideIncreased PermeabilityGastroenterologyLow Extracellular PhDigestive Tract +20

Abnormalities of cytoplasmic Ca2+ in platelets from patients with uremia

JA Ware, BA Clark, M. Smith, +1

Blood

Inhibition of human platelet aggregation and cytoplasmic calcium response by calcium antagonists: studies with aequorin and quin2.

J. Anthony Ware, Peter C. Johnson, M. Smith, +1

Circulation Research

PharmacotherapyPlatelet AggregationCellular PhysiologyMolecular PharmacologyThrombosis +14