Guofeng Chen

Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial

Yining Huang, Richard I. Lindley, Xiaoying Chen et al. · The Lancet · 2019 · 271 citations · Full text

Medicine, Cardiology, Pharmacotherapy +13

Efficacy and safety of 3-week response-guided triple direct-acting antiviral therapy for chronic hepatitis C infection: a phase 2, open-label, proof-of-concept study

George Lau, Yves Benhamou, Guofeng Chen et al. · ˜The œLancet. Gastroenterology & hepatology · 2016 · 94 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +13

Single-Cell Profiling of Tumor Immune Microenvironment Reveals Immune Irresponsiveness in Gastric Signet-Ring Cell Carcinoma

Jing Chen, Kuai Liu, Yikai Luo et al. · Gastroenterology · 2023 · 76 citations · Full text

Medicine, Immunology, Oncology +17

Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer

Yu Jiang, Yawen Wang, Guofeng Chen et al. · Cell Metabolism · 2024 · 70 citations · Full text

Medicine, Cancer Biology, Oncology +17

Loss of p53 and altered miR15-a/16-1→MCL-1 pathway in CLL: insights from TCL1-Tg:p53−/− mouse model and primary human leukemia cells

Jinyun Liu, Guofeng Chen, Lei Feng et al. · Leukemia · 2013 · 58 citations

Life Sciences, Molecular Biology, Oncology +16