Cisplatin Inhibits Protein Splicing, Suggesting Inteins as Therapeutic Targets in Mycobacteria

Liyun Zhang, Yuchuan Zheng, Brian P. Callahan, +2

Journal of Biological Chemistry

Molecular BiologyEscherichia ColiAnticancer Drug CisplatinSplicing VariantTranscriptional Regulation +15

p<i>K</i>_a Coupling at the Intein Active Site: Implications for the Coordination Mechanism of Protein Splicing with a Conserved Aspartate

Zhenming Du, Yuchuan Zheng, Melissa N. Patterson, +2

Journal of the American Chemical Society

Protein ChemistrySequential ProtonationC1 ThiolateProtein FunctionBiochemistry +10

Binding and Inhibition of Copper Ions to RecA Inteins from <i>Mycobacterium tuberculosis</i>

Liyun Zhang, Ning Xiao, Yan Pan, +5

Chemistry - A European Journal

Protein ChemistryPulmonary TuberculosisReca InteinsBiochemistryIntein Splicing +12

Metal ions binding to recA inteins from <i>Mycobacterium</i> <i>tuberculosis</i>

Liyun Zhang, Yuchuan Zheng, Zhaoyong Xi, +4

Molecular BioSystems

Mutual synergistic protein folding in split intein

Yuchuan Zheng, Qin Wu, Chunyu Wang, +2

Bioscience Reports

Favourable Enthalpy ChangeProtein ChemistryProtein AssemblyBiochemistryProtein Folding +10

Highly selective detection of nitroaromatic explosive 2,4,6-trinitrophenol (TNP) using N-doped carbon dots

Yuchuan Zheng, Shu Wang, Ruifeng Li, +4

Research on Chemical Intermediates

Chemical EngineeringEngineeringExplosive ChemistryOrganic ChemistryAnalytical Chemistry +4

A novel colorimetric chemosensor for Cu2+ with high selectivity and sensitivity based on Rhodamine B

Changjiang Li, Kaiqiang Xiang, Yunchang Liu, +3

Research on Chemical Intermediates

Materials ScienceChemical EngineeringRhodamine BEngineeringPhotochemistry +6

Cisplatin Preferentially Binds to Zinc Finger Proteins Containing C3H1 or C4 Motifs

Siming Yuan, Xin Ding, Yang Cui, +3

European Journal of Inorganic Chemistry

Protein SelectivityCisplatin Preferentially BindsMolecular BiologyZinc Finger ProteinsChemical Biology +18

A colorimetric and fluorescent chemodosimeter responding to Cu2+ with high selectivity and sensitivity

Changjiang Li, Kaiqiang Xiang, Yunchang Liu, +4

Research on Chemical Intermediates

PhotochemistryFluorescent ChemodosimeterNatural SciencesSpectroscopyBioimaging +7

Tetrathiomolybdate inhibits the reaction of cisplatin with human copper chaperone Atox1

Yao Tian, Tiantian Fang, Siming Yuan, +4

Metallomics