J. Hope

The major polypeptide of scrapie‐associated fibrils (SAF) has the same size, charge distribution and N‐terminal protein sequence as predicted for the normal brain protein (PrP).

J. Hope, L.J. Morton, Christine Farquhar et al. · The EMBO Journal · 1986 · 325 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Two alleles of a neural protein gene linked to scrapie in sheep.

Wilfred Goldmann, Nora Hunter, James D. Foster et al. · Proceedings of the National Academy of Sciences · 1990 · 302 citations · Full text

Veterinary Medicine, Genetics, Molecular Genetics +15

Transmission of bovine spongiform encephalopathy to sheep and goats

JD Foster, J. Hope, H. Fraser · Veterinary Record · 1993 · 287 citations

Veterinary Medicine, Animal Sciences, Infectious Diseases +10

PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology.

Jean Manson, Alan R. Clarke, Patricia McBride et al. · PubMed · 1994 · 269 citations

Veterinary Medicine, Molecular Biology, Molecular Genetics +13

Molecular analysis of ovine prion protein identifies similarities between BSE and an experimental isolate of natural scrapie, CH1641

J. Hope, Sophie Wood, M. E. Bruce et al. · Journal of General Virology · 2000 · 154 citations

Veterinary Medicine, Infectious Diseases, Neurology +17