Wen‐Liang Dong

Synthesis of novel substituted pyrazole-5-carbohydrazide hydrazone derivatives and discovery of a potent apoptosis inducer in A549 lung cancer cells

Liang‐Wen Zheng, Lingling Wu, Bao‐Xiang Zhao et al. · Bioorganic & Medicinal Chemistry · 2009 · 160 citations

Life Sciences, Medicinal Chemistry, Pharmacology +11

Synthesis and preliminary biological evaluation of novel pyrazolo[1,5-a]pyrazin-4(5H)-one derivatives as potential agents against A549 lung cancer cells

Jinhua Zhang, Chuandong Fan, Bao‐Xiang Zhao et al. · Bioorganic & Medicinal Chemistry · 2008 · 53 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Novel indolyl-chalcone derivatives inhibit A549 lung cancer cell growth through activating Nrf-2/HO-1 and inducing apoptosis in vitro and in vivo

Xuan Zhao, Wen‐Liang Dong, Yuandi Gao et al. · Scientific Reports · 2017 · 44 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

ORCA-010, a Novel Potency-Enhanced Oncolytic Adenovirus, Exerts Strong Antitumor Activity in Preclinical Models

Wen‐Liang Dong, J. H. van Ginkel, Kam Y. Au et al. · Human Gene Therapy · 2014 · 34 citations · Full text

Medicine, Oncology, Pharmacology +12

Synthesis and discovery of autophagy inducers for A549 and H460 lung cancer cells, novel 1-(2′-hydroxy-3′-aroxypropyl)-3-aryl-1H-pyrazole-5-carbohydrazide derivatives

Chuandong Fan, Bao‐Xiang Zhao, Fang Wei et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 31 citations

Life Sciences, Medicinal Chemistry, Oncology +14