Helen Jiang

Disruption of the Y-Box Binding Protein-1 Results in Suppression of the Epidermal Growth Factor Receptor and HER-2

Joyce C. Wu, Cathy Lee, Daniel Yokom et al. · Cancer Research · 2006 · 156 citations

Breast Oncology, Human Growth, Cell Growth +18

Epidermal growth factor receptor (EGFR) is transcriptionally induced by the Y-box binding protein-1 (YB-1) and can be inhibited with Iressa in basal-like breast cancer, providing a potential target for therapy

Anna L. Stratford, Golareh Habibi, Arezoo Astanehe et al. · Breast Cancer Research · 2007 · 145 citations · Full text

Profiling YB-1 target genes uncovers a new mechanism for MET receptor regulation in normal and malignant human mammary cells

Melanie Finkbeiner, Arezoo Astanehe, Karen To et al. · Oncogene · 2009 · 94 citations

Breast Oncology, Signaling Pathway, Met Receptor Regulation +9

The Phosphoinositide-Dependent Kinase-1 Inhibitor 2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]-acetamide (OSU-03012) Prevents Y-Box Binding Protein-1 from Inducing Epidermal Growth Factor Receptor

Karen To, Yi Zhao, Helen Jiang et al. · Molecular Pharmacology · 2007 · 33 citations