Lei Xu

DSCAM/PAK1 pathway suppression reverses neurogenesis deficits in iPSC-derived cerebral organoids from patients with Down syndrome

Xiaoyan Tang, Lei Xu, Jingshen Wang et al. · Journal of Clinical Investigation · 2021 · 131 citations · Full text

Loss of deubiquitylase USP2 triggers development of glioblastoma via TGF-β signaling

Yiming Tu, Lei Xu, Jia Xu et al. · Oncogene · 2022 · 30 citations

Developmental Biology, Signaling Pathway, Glioma +7

Nanoplastics exposure-induced mitochondrial dysfunction contributes to disrupted stem cell differentiation in human cerebral organoids

Mengdan Tao, Can Wang, Zhilong Zheng et al. · Ecotoxicology and Environmental Safety · 2024 · 27 citations · Full text

Neuroregeneration, Medicine, Stem Cell Differentiation +8

Abnormal mitochondria in Down syndrome iPSC-derived GABAergic interneurons and organoids

Lei Xu, Hai-Qin Huo, Kaiqin Lu et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2022 · 22 citations

Down Syndrome, Developmental Biology, Molecular Neuroscience +7

Artificial Meshed Vessel-Induced Dimensional Breaking Growth of Human Brain Organoids and Multiregional Assembloids

Lei Xu, Haibo Ding, Shanshan Wu et al. · ACS Nano · 2024 · 13 citations · Full text