Yanxing Wang

DeepScaffold: A Comprehensive Tool for Scaffold-Based De Novo Drug Discovery Using Deep Learning

Yibo Li, Jianxing Hu, Yanxing Wang et al. · Journal of Chemical Information and Modeling · 2019 · 151 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11

Inactivation of rabbit muscle glycogen synthase by glycogen synthase kinase-3. Dominant role of the phosphorylation of Ser-640 (site-3a).

Yanxing Wang, Peter J. Roach · Journal of Biological Chemistry · 1993 · 68 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Multistage Screening Reveals 3-Substituted Indolin-2-one Derivatives as Novel and Isoform-Selective c-Jun N-terminal Kinase 3 (JNK3) Inhibitors: Implications to Drug Discovery for Potential Treatment of Neurodegenerative Diseases

Xiaodong Dou, Huixia Huang, Yibo Li et al. · Journal of Medicinal Chemistry · 2019 · 57 citations · Full text

Pharmacy, Medicinal Chemistry, Neuroscience +17

Current Trends and Challenges in Drug-Likeness Prediction: Are They Generalizable and Interpretable?

Wenyu Zhu, Yanxing Wang, Yan Niu et al. · Health Data Science · 2023 · 29 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Discovery of novel glycogen synthase kinase-3α inhibitors: Structure-based virtual screening, preliminary SAR and biological evaluation for treatment of acute myeloid leukemia

Yanxing Wang, Xiaodong Dou, Lan Jiang et al. · European Journal of Medicinal Chemistry · 2019 · 23 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +12