Dysregulation of TGF-β1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice

Xiangchun Wang, Shinya Inoué, Jianguo Gu, +23

Proceedings of the National Academy of Sciences

Inflammatory Lung DiseaseAdvanced Lung DiseaseLung InflammationImmunologyCell Death +22

Attenuation of pulmonary ACE2 activity impairs inactivation of des-Arg⁹bradykinin/BKB1R axis and facilitates LPS-induced neutrophil infiltration

Chhinder P. Sodhi, Christine Wohlford-Lenane, Yukihiro Yamaguchi, +7

American Journal of Physiology-Lung Cellular and Molecular Physiology

Toll-like receptor 4–mediated lymphocyte influx induces neonatal necrotizing enterocolitis

Charlotte E. Egan, Chhinder P. Sodhi, Misty Good, +12

Journal of Clinical Investigation

Microbial PathogensInnate Immune SystemImmunologyImmune RegulationRetinoic Acid +17

Breast milk protects against the development of necrotizing enterocolitis through inhibition of Toll-like receptor 4 in the intestinal epithelium via activation of the epidermal growth factor receptor

Misty Good, Chhinder P. Sodhi, C E Egan, +12

Mucosal Immunology

InflammationMucosal ImmunologyLactationPathogenesisImmunology +9

The human milk oligosaccharides 2’-fucosyllactose and 6’-sialyllactose protect against the development of necrotizing enterocolitis by inhibiting toll-like receptor 4 signaling

Chhinder P. Sodhi, Peter Wipf, Yukihiro Yamaguchi, +14

Pediatric Research

Mucosal Immunology’ -FucosyllactoseMedicineInnate Immune SystemImmunology +7

Toll-like Receptor 4-mediated Endoplasmic Reticulum Stress in Intestinal Crypts Induces Necrotizing Enterocolitis

Amin Afrazi, Maria Branca, Chhinder P. Sodhi, +22

Journal of Biological Chemistry

The human milk oligosaccharide 2′-fucosyllactose attenuates the severity of experimental necrotising enterocolitis by enhancing mesenteric perfusion in the neonatal intestine

Misty Good, Chhinder P. Sodhi, Yukihiro Yamaguchi, +12

British Journal Of Nutrition

Cognitive impairments induced by necrotizing enterocolitis can be prevented by inhibiting microglial activation in mouse brain

Diego F. Niño, Qinjie Zhou, Yukihiro Yamaguchi, +18

Science Translational Medicine

Clinical and Molecular Characteristics of Klebsiella pneumoniae Isolates Causing Bloodstream Infections in Japan: Occurrence of Hypervirulent Infections in Health Care

Sohei Harada, Kotaro Aoki, Shungo Yamamoto, +24

Journal of Clinical Microbiology

A Dynamic Variation of Pulmonary ACE2 Is Required to Modulate Neutrophilic Inflammation in Response to <i>Pseudomonas aeruginosa</i> Lung Infection in Mice

Chhinder P. Sodhi, Jenny Nguyen, Yukihiro Yamaguchi, +13

The Journal of Immunology

Acute Lung InjuryInflammatory Lung DiseaseLung InflammationImmunologyDynamic Variation +15