Yanyan Diao

Novel Selective and Potent Inhibitors of Malaria Parasite Dihydroorotate Dehydrogenase: Discovery and Optimization of Dihydrothiophenone Derivatives

Minghao Xu, Junsheng Zhu, Yanyan Diao et al. · Journal of Medicinal Chemistry · 2013 · 59 citations · Full text

Bioorganic Chemistry, Antiparasitic Agent, Malaria +16

Discovery of Diverse Human Dihydroorotate Dehydrogenase Inhibitors as Immunosuppressive Agents by Structure-Based Virtual Screening

Yanyan Diao, Weiqiang Lü, Huangtao Jin et al. · Journal of Medicinal Chemistry · 2012 · 56 citations · Full text

Drug Target, Hit Identification, Malaria +23

Design, Synthesis, X-ray Crystallographic Analysis, and Biological Evaluation of Thiazole Derivatives as Potent and Selective Inhibitors of Human Dihydroorotate Dehydrogenase

Junsheng Zhu, Le Han, Yanyan Diao et al. · Journal of Medicinal Chemistry · 2015 · 54 citations · Full text

Medicinal Chemistry, Pharmaceutical Science, Derivative (Chemistry) +15

Macrocyclization of linear molecules by deep learning to facilitate macrocyclic drug candidates discovery

Yanyan Diao, Dandan Liu, Huan Ge et al. · Nature Communications · 2023 · 46 citations · Full text

Drug Target, Computational Macrocyclization Method, Engineering +20

New aromatic substituted pyrazoles as selective inhibitors of human adipocyte fatty acid-binding protein

Xiujie Liu, Xiaoli Huang, Wanhua Lin et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 29 citations · Full text

Biochemistry, Medicine, Rational Drug Design +5