J. J. Singh

DcpS as a Therapeutic Target for Spinal Muscular Atrophy

J. J. Singh, Michael Salcius, Shin-Wu Liu et al. · ACS Chemical Biology · 2008 · 132 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +14

Effects of 2,4-diaminoquinazoline derivatives on SMN expression and phenotype in a mouse model for spinal muscular atrophy

Matthew E.R. Butchbach, J. J. Singh, Margrét Þorsteinsdóttir et al. · Human Molecular Genetics · 2009 · 119 citations · Full text

Life Sciences, Molecular Genetics, Neuroscience +12

Synthesis and Biological Evaluation of Novel 2,4-Diaminoquinazoline Derivatives as <i>SMN2</i> Promoter Activators for the Potential Treatment of Spinal Muscular Atrophy

John B. Thurmond, Matthew E.R. Butchbach, Marty Palomo et al. · Journal of Medicinal Chemistry · 2008 · 92 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

The DcpS inhibitor RG3039 improves survival, function and motor unit pathologies in two SMA mouse models

Rocky G. Gogliotti, Herminio J. Cardona, J. J. Singh et al. · Human Molecular Genetics · 2013 · 88 citations · Full text

Medicine, Neuroscience, Pharmacology +17

The Adrenocorticotropin Response to Interleukin-1β Instilled into the Rat Median Eminence Depends on the Local Release of Catecholamines*

Shannon G. Matta, J. J. Singh, Robert Newton et al. · Endocrinology · 1990 · 82 citations

Life Sciences, Endocrinology, Physiology +16