Roberto Gómez

CIGB-300, a novel proapoptotic peptide that impairs the CK2 phosphorylation and exhibits anticancer properties both in vitro and in vivo

Silvio E. Perea, Osvaldo Reyes, Idania Baladrón et al. · Molecular and Cellular Biochemistry · 2008 · 99 citations

Ck2 Phosphorylation, Novel Proapoptotic Peptide, Signal Transduction +11

Hepatitis B vaccination results in 140 liver transplant recipients.

Carmelo Loinaz, J.R. de Juanes, E. Moreno González et al. · PubMed · 1997 · 99 citations

Safety and preliminary efficacy data of a novel Casein Kinase 2 (CK2) peptide inhibitor administered intralesionally at four dose levels in patients with cervical malignancies

Ana M. Solares, Agueda Santana, Idania Baladrón et al. · BMC Cancer · 2009 · 80 citations · Full text

Anticancer peptide CIGB-300 binds to nucleophosmin/B23, impairs its CK2-mediated phosphorylation, and leads to apoptosis through its nucleolar disassembly activity

Yasser Perera, Hernán G. Fariña, Jeovanis Gil et al. · Molecular Cancer Therapeutics · 2009 · 71 citations · Full text

Apoptosis, Immunology, Cell Death +18

Systemic administration of a peptide that impairs the protein kinase (CK2) phosphorylation reduces solid tumor growth in mice

Yasser Perera, Hernán G. Fariña, Ignacio Hernández et al. · International Journal of Cancer · 2007 · 64 citations · Full text