Silvio E. Perea

Antitumor Effect of a Novel Proapoptotic Peptide that Impairs the Phosphorylation by the Protein Kinase 2 (Casein Kinase 2)

Silvio E. Perea, Osvaldo Reyes, Yaquelín Puchades et al. · Cancer Research · 2004 · 163 citations

Life Sciences, Cancer Biology, Oncology +17

CIGB-300, a novel proapoptotic peptide that impairs the CK2 phosphorylation and exhibits anticancer properties both in vitro and in vivo

Silvio E. Perea, Osvaldo Reyes, Idania Baladrón et al. · Molecular and Cellular Biochemistry · 2008 · 101 citations

Life Sciences, Cell Biology, Molecular Biology +8

Safety and preliminary efficacy data of a novel Casein Kinase 2 (CK2) peptide inhibitor administered intralesionally at four dose levels in patients with cervical malignancies

Ana M. Solares, Agueda Santana, Idania Baladrón et al. · BMC Cancer · 2009 · 80 citations · Full text

Medicine, Oncology, Pharmacology +6

Anticancer peptide CIGB-300 binds to nucleophosmin/B23, impairs its CK2-mediated phosphorylation, and leads to apoptosis through its nucleolar disassembly activity

Yasser Perera, Hernán G. Fariña, Jeovanis Gil et al. · Molecular Cancer Therapeutics · 2009 · 72 citations · Full text

Life Sciences, Biochemistry, Oncology +17

Human papillomavirus type 16 E7 impairs the activation of the interferon regulatory factor-1.

Silvio E. Perea, Paola Massimi, Lawrence Banks · International Journal of Molecular Medicine · 2000 · 70 citations

Life Sciences, Genetics, Molecular Biology +17