Induced disruption of the transforming growth factor beta type II receptor gene in mice causes a lethal inflammatory disorder that is transplantable

Per Levéen, Jonas Larsson, Mats Ehinger, +5

Blood

Signaling via the Tgf-β type I receptor Alk5 in heart development

Somyoth Sridurongrit, Jonas Larsson, Robert J. Schwartz, +2

Developmental Biology

Cardiac MuscleCardiomyopathyDevelopmental BiologyMolecular PhysiologySignal Transduction +8

TGF-β signaling–deficient hematopoietic stem cells have normal self-renewal and regenerative ability in vivo despite increased proliferative capacity in vitro

Jonas Larsson, Ulrika Blank, Hildur Helgadóttir, +6

Blood

Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia

Pekka Jaako, Johan Flygare, Karin Olsson, +10

Blood

Reduced Proliferative Capacity of Hematopoietic Stem Cells Deficient in<i>Hoxb3</i>and<i>Hoxb4</i>

Jon Mar Bjürnsson, Nina Larsson, Ann Brun, +8

Molecular and Cellular Biology

GeneticsStem Cell BiologyEmbryologyStem Cell MobilizationHematology +14

Activation of neuronal genes via LINE-1 elements upon global DNA demethylation in human neural progenitors

Marie E. Jönsson, Per Ludvik Brattås, Charlotte Gustafsson, +10

Nature Communications

Hepatic Leukemia Factor Maintains Quiescence of Hematopoietic Stem Cells and Protects the Stem Cell Pool during Regeneration

Karolina Komorowska, Alexander Doyle, Martin Wahlestedt, +10

Cell Reports

Lymphocyte DevelopmentAdult Stem CellImmunologyCell ProliferationHlf-deficient Mice +17

Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction

Susana M. Chuva de Sousa Lopes, A. Feijen, Jeroen Korving, +8

Developmental Dynamics

Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects

Jikui Wang, Andre Nagy, Jonas Larsson, +3

BMC Developmental Biology

Genome-wide RNAi Screen Identifies Cohesin Genes as Modifiers of Renewal and Differentiation in Human HSCs

Roman Galeev, Aurélie Baudet, Praveen Kumar, +7

Cell Reports